Protect

The project is entitled : « Risk of malaria in children who have reached the age of Five Years and are no longer eligible for Seasonal Malaria Chemoprevention (SMC) and or Seasonal Malaria Vaccination in Burkina Faso and Mali »

Current effective malaria control tools include seasonal malaria chemoprevention (SMC) tailored for the countries of the Sahel and Sub Sahel. SMC involves the administration of full therapeutic doses of sulfadoxine-pyrimethamine plus amodiaquine once monthly over the highest malaria transmission period. The RTS,S/AS01 vaccine is given three times as a priming course followed by one booster over three years. The vaccine RTS,S/AS01 induces high immunogenicity with production of antibodies against the Circumsporozoîte (csp) protein of Plasmodium falciparum resulting in partial protection against malaria; seasonal use of this vaccine may add to the protection afforded by SMC.